IC433 is a supernova remnant of a star which exploded about 35000 years ago. It is located approx. 5000 light years away. To the left is Sharpless 249, a large emission nebula, which also contains the small reflection nebula IC444( small blueish patch in the upper middle).
The two bright stars are Eta and Mu Geminorum.
The image was NASA's APOD on 14-MAY-2009: http://apod.nasa.gov/apod/ap090514.html